The problem with using them is that it’s pretty inefficient to provide 120 volts for the mini’s power supply, only to down convert the voltages to what the logic board and components use. You’ll need way more mAh than you’d need to just power a MacBook.
It isn't 2002. Laptops with features comparable to desktops do not require a three point lifting harness and a recurring appointment with a chiropractor.
For reference, I've used a desktop as my primary workstation since late 2018. For the ~decade before that I used a laptop as my primary workstation.