Here are a few Qs to discover your blind spots: Have you spoken to the large industrial employers in your region? The nearest hospital? The fastest growing companies in your state? The businesses that sponsor local sporting events and festivals? Have you looked out of area? Tried contract work? Gotten feedback from a recruiter? Asked a prof if they can introduce you to anyone? Called the mayor? Schmoozed at a Chamber of Commerce meeting?
Half these things may sound uncomfortable and awkward, but I guarantee you won't get through the list without being offered a job. Put yourself out there in multiple ways.
Put all gains towards a safety fund (enough to support your expenses for 3 months) first, and after that fully towards paying debt back, until you have paid it in full.
A pain, but that's life. Sometimes, you just have to grind. In the future, you'll be glad you got rid of debt and your struggles are behind you.
If your huge bill refers to student loans, there are some good options now, especially if you're not bringing in much (or any) money. The big advantage of the new SAVE program over previous income-based plans is that your loan balances do not accrue interest. If worst comes to worst, and you wind up working at a 7-11 or something, you likely won't have to pay anything until your financial situation improves (nor will your balance increase due to unpaid interest).
Check it out before you panic. :-)
https://www2.ed.gov/policy/highered/reg/hearulemaking/2021/i...
Also, those of us who've been around for a while have seen more than one of these temporary downturns. They always go away after a while.
Best of luck!