HACKER Q&A
📣 speedylight

What is your experience with Nano-Hydroxyapatite toothpaste?


I have really bad tooth sensitivity and I recently learned about n-Ha toothpaste being a solid treatment for it (mainly the one Boka sells) The fact that n-Ha is the compound that enamel is made of seems really promising but I don’t know enough about it to know if it’ll work and it’s really hard to trust product reviews. Money is in short supply so I really want to make sure I’m not buying into a fad.

I know you all are not dentists or chemists (I’m assuming anyway), but we’ll have the same teeth, so if you happened to use it for a similar purpose and saw good results, I want to know about your experience.

Thank you all.


  👤 lumb63 Accepted Answer ✓
Have tried Boka, Apagard, David’s, and Elims. I have come to much prefer the lack of foaming (I think due to SLS) and they’ve helped my sensitivity slightly. I would recommend them to anyone over fluoride toothpastes due to the possible neurotoxicity of the latter, especially for children.

👤 Moldoteck
Bought both apagard royal and apagard premio. I like the taste much more compared to classic ones, but I can't say I've seen some improvements in my teeth, looks the same as when I used Splat or Sesnsodyne protect&repair.

Also, consider that apagard usually doesn't have compounds that make your teeth less sensible like other toothpaste

Also, fyi- you should not wash your mouth after brushing, just spit the extra paste and wash after ~10-20 mins, this is valid for fluoride variations too

Anyway, just buy a tube (start with premio) and see how it goes


👤 j-bos
I'm curious too, so this is more a piggybacking question: Silver diamine is said to be the perfect cavity treatment, cheap, fast, and effective with the only downside being staining of the teeth. Does anyone on HN have silver diamine experiences to share?

👤 abrichr
I use MI Paste. I don't brush with it. Instead I place it in custom teeth whitening trays and let it sit for an hour or so. It's very helpful for reducing sensitivity!

I also have Curodont Protect, but haven't tried it yet.

Curious to hear others' experiences!


👤 anizan
Use GC tooth Mousse which is a Japanese product and a well kept secret. My dentist suggested it as the only product with actual results on rebuilding enamel. Most Dentists in USA don't promote this keeping in mind their incentives and it's a 30 year old technology with great results. Pubmed has loads of studies you can pursue. It worked wonders for me.

https://www.amazon.com/TOOTH-MOUSSE-X40GM-DENTAL-PRODUCT/dp/...

There's a newer version called Mi paste which is distributed. https://www.gc.dental/america/products/operatory/preventive/...


👤 ahoka
It cured my baldness.

👤 rjzzleep
In the US and Germany they say there is no solid evidence suggesting that they keep what they promise. I personally use what seems to be an Italian brand called Biorepair and they clearly help with my tooth sensitivities(I have a bad habit of chewing on my nails when stressed).

Biorepair seems to have split into an Italian version and a German version with less active ingredients called Bioniq. The Italian versions seems to add xylitol.

https://www.amazon.com/s?k=biorepair&i=hpc&crid=3BEZX0VR8DUD...


👤 bionhoward
Mechanistically, it makes sense. Fluoride is intended to perform a similar role of strengthening the enamel, so it makes sense to directly use the enamel substance as a paste to provide tooth regrowth materials at the site they’re needed. It has helped me with some tooth issues.

Research hydroxyapatite toothpaste prevents cavities: https://www.frontiersin.org/articles/10.3389/fpubh.2023.1199...

In kids: https://www.nature.com/articles/s41598-021-81112-y

Research the same regenerates tooth enamel: https://jnanobiotechnology.biomedcentral.com/articles/10.118...

Another thing which is extremely helpful and I wish I had begun much earlier in life is night mouthguards because grinding your teeth in your sleep even in a subtle way does add up over years and years.


👤 Podgajski
Hey, you know what fixed my tooth sensitivity? Sucking on calcium carbonate tablets, like Tums. The calcium will enter the microtubules and remineralize the teeth.

https://www.sciencedirect.com/science/article/pii/S199179021...


👤 Faaak
You should also try Sensodyne repair and protect. I heard it's not available in the US, but the EU ones contain Novamin which really helps sensitive tooth.

👤 pps
https://www.apacare.com/Remineralising-Toothpaste/1001619

I’ve been using this toothpaste for years and it completely cured my tooth sensitivity issues. I buy it online from the Polish equivalent of Amazon. Looking at people’s reviews, the overwhelming majority are positive, but there are also some negative ones, so it’s definitely not a miracle product.


👤 Perceval
I have been using Dr. Jen's Super Paste: https://drjennatural.com/products/dr-jen-super-paste-with-na...

I landed on this one out of all the N-Ha brands because it also has flouride. Also, it doesn't have SLS, which I feel good about.

I used to need Sensodyne to manage tooth sensitivity. I would go out of my way to buy Canadian or UK Sensodyne with Novamin, since the Novamin formulations aren't sold in the U.S. However, Jen's has eliminated the tooth sensitivity without needing a numbing agent like Sensodyne, which was surprising to me.

I've stuck with Jen's even though it's more expensive. I can't speak to whether it's strengthened my enamel appreciably, but my teeth feel much better.


👤 DantesKite
Lots of Vitamin D and Vitamin K2 removed most if not all of my tooth sensitivity over the course of a month.

About 5 normal Vitamin D pills every few days so.

I was trying to treat something else out of desperation and noticed my tooth sensitivity more or less vanished.

Which makes sense when considering their role.

But as always, n=1.


👤 bilsbie
Is this the same as novamin? If not which might be better?

👤 fallinghawks
To be fair I don't really have any real problems with my teeth apart from having had an overeager/greedy childhood dentist who put in a ton of fillings, making for a lifetime of occasionally having to redo one and needing 2 crowns.

I switched to Apagard about 8 months ago. My hygienist seemed happy about it. I like the fact that it's not overwhelmingly minty like most American toothpastes and doesn't foam up too much. I think if I manage to avoid needing new fillings or a redo for 6-7 years (about the frequency at which I need one) I would consider it a good switch.


👤 darkhorn
Don't drink soda. Drink water.It will create a protective layer for few hours.

👤 navjack27
I use a sensodyne toothpaste that has biomin in it. I'm not good about brushing and every once in a while the right side of my face hurts around my upper or lower molars or something and I'll remember to brush again and take an Aleve and it goes away within a day or two.

👤 speedylight
I’m so glad I made this thread, a wealth of information and recommendations from many people. I no longer feel my situation is hopeless, thank you guys.

👤 esaym
Use Sensodyne with novamin. You can get the Canadian version on ebay.

👤 theNJR
Since we are talking dental health, any insights into gingival recession? I think my gums have receded due to brushing them too hard over the years. You can’t tell unless you flip my gums back.

👤 34823054950
Since no one's mentioned it yet - I had really sensitive gums for a while, and it was because I was very anemic, after the anemia was dealt with the sensitivity was gone. So if you have other symptoms of anemia also (fatigue, random dizziness, wanting to chew ice, etc) & haven't had it checked in a while maybe ask your doctor about it.

👤 hackily
I use apagard premio, came across it while doing research a couple of years ago (4-5) on nano hydroxyapatite. I've never really had problems with my adult teeth and I continue to not have problems, so at the very least, in my case, is not any worse than fluoride toothpaste. My dentist loves my teeth :D she told me whatever I'm doing, don't change a single thing.

👤 Anaid__
I've been using a tooth paste with hydroxypatite for a little more than one year. Mostly for the enamel in my front teeth. I can see it works to some extend. The corrosion from the upper side of the teeth have stopped and I can see improvement of the already eroded side but I am talking about less than a milimiter. It is not a quick solution, and it requires dental higyne routinely. As for the price, I found that of you get the tooth paste in bulk it is more affordable.

👤 bookmtn
On the topic of toothpaste, I developed a reaction to SLS - Sodium Laurel Sulfate. That's when I switched to Sensodyne, because it doesn't contain SLS. For awhile, Sensodyne was a problem and I began using Baking Soda. Then returned to Sensodyne after a few weeks.

Before this sensitivity, someone asked if I whitened my teeth because they were whiter. Using an electric toothbrush changed the color of my teeth for the better.

A Water-Pik helps the gums rejuvenate as does flossing.


👤 electrondood
While we're here, I'd like to point out that the medium chain triglycerides in coconut oil are AS EFFECTIVE of an antimicrobial as the most common prescription dental mouthwash Chlorhexidine [0].

[0] https://pubmed.ncbi.nlm.nih.gov/27891311/#:~:text=The%20stud....


👤 artificialLimbs
When my teeth get too sensitive I swish with clove oil and that works well. I put a couple drops of oil in the bottom of a glass and fill it with about a cup of water.

👤 beaugunderson
Had been using Apagard Premio n-Ha toothpaste since 2020. Ended up with 8 cavities in early 2023, largely due to two factors: consistently drinking one sugar free Red Bull in the morning, my critical error here was in drinking it SLOWLY over the course of one hour... no one ever taught me about the Stephan curve or why keeping your mouth in an acidic state could be disastrous for your teeth. The other factor was grinding my teeth at night, and a bite guard has somewhat helped there. Ideal would be not grinding but I don't have a magic solution there. Dentist prescribed fluoride toothpaste and MI paste. My tooth sensitivity is now gone.

👤 stevenae
I started using Uncle Harry's, after having a sensitive crisis and being told by a dentist that I would need extensive crowns. That was... 7 years ago? Got one cavity done last year.

Surprised no one else had mentioned them. American, reputable, easy to find.


👤 kukkeliskuu
I have tried Boka, but ultimately decided to stop using it. Don’t really have enough data to recommend or not recommend it. I have used BioPure ozone ooth paste and that is excellent, just dfficult to get to the EU. https://store.biopureus.com/products/tooth-and-gum-paste?var...

👤 an_aparallel
There are spot treatments which general dentists do not have access to - which you must go to a periodontist for. My back molar had some bad sensitivity - and i could not risk loosing it before a major dental surgery - so i had this treatment done. These spot treatments (topical) last for 4-6 months. Going to a perio will cost you though (obviously)