HACKER Q&A
📣 dustfinger

Have you taken anti-aging supplements that reduced biological age?


I am curious to hear from anyone that has tried anti aging supplements and observed a measurable reduction in their biological age as a direct result of the supplements? I am equally interested in hearing from those that tried these, or similar supplements with no measurable reduction in biological age.

For those that observed a measurable reduction in biological age:

    - What were the supplements & dosage?
    - What was the measurable improvement?
Examples of such supplements:

    Nicotinamide mononucleotide (NMN)
    Resveratrol
    Metformin
    Statin
    Alpha lipoic acid (ALA)
    Coenzyme Q10 (coQ10)
    Spermidine
    Quercetin and fisetin
    TMG (trimethylglycine or betaine)

  👤 jyu Accepted Answer ✓
Just a small warning. These supplements are less impactful than optimized sleep, exercise, diet, stress related to work or personal. It's difficult to change 1 variable while holding the others stable.

I have also found measuring and interpreting different biomarkers nontrivial.

Watching Michael Lustgarten's efforts is very relevant https://www.youtube.com/@conqueragingordietrying1797

👤 gfd
For skin, retinoids seem to work well. You can order one called Differin w/o prescription
👤 yamrzou
If you're interested in longevity, I recommend the book “Outlive: The Science and Art of Longevity” by Peter Attia MD.
👤 croo
If you are looking for a younger look, excercises exists that will stress your facial muscles. With a few months of training you can get a younger look. Of course that won't get you to live longer :)