Another ridiculous one that comes to mind is longer-timeframe economic developments, for example in asset prices recently you can find clear opportunities at longer time frames but can and will watch those prices perform counter to your model on lower time frames. Or an economic intervention is put into place but the results won't be seen clearly for 5Y at least.
This ends up forcing special qualitative, probabilistic risk models to work too hard compared to rational decision-making, and humans are in such a case far better at the latter.
While that's kind of a "the way things just are, things take time" situation, I also get the notion that something can be done about it.
The shift towards capability based security away from User accounts and ACLs is about 20 years behind in my estimation.
When turning it back on in the morning, it takes a minute for the whole thing to get online. I've often wondered why it takes that long; can't it happen in a few seconds?