What anti-aging technologies will be available in 20-30 years, and what can I do today to prepare to derive maximum benefit from them when they arrive?
I’m looking for answers beyond the obvious exercise and be healthy, although I should probably start with that. :)
Let's suppose that real results come out of current research into NAD-boosting and other methods for reducing defects when cells split and for reducing senescence of cells. That would extend your potential lifetime but you can still die from accidents/violence, cancer, and diseases incl heart disease, so you need to take preventative measures for those factors.
David Sinclair suggests that you should cut sugar/desserts from your diet (because it encourages cell splitting), and reduce damage to your body, e.g. use sunscreen (because cell defects arise when repairing cell damage).
If humans could grow biblically old, like 600-900 years, one thing to consider is it's possible they might start looking like Ferengi, since cartilage just keeps growing.
Human trials are expensive and obviously take multiple decades, so you’ll be dead before to see that data.
The compounds so far are:
rapamycin, acarbose, 17-alpha-estradiol, canagliflozin, asthaxanthin, meclizine
I will believe it's actually starting to happen when it becomes possible to pay money to get new hair (not hair transplants, or blocking DHT). Hair is infinitely simpler than repairing complex organs and we can't even do that.
Artificial organs appear much more achievable - as in only requiring investments into engineering problems rather than completely new discoveries.
Type 2 diabetics on metformin live 15% longer than non-diabetics. This is remarkable considering how big a health disadvantage diabetes itself is.
Metformin seems to mimic fasting somehow, by interfering with mitochondrial function.
For more information I refer you to David Sinclair's numerous discussions on this topic. He takes 1 gram of metformin per day with his evening meal.
This is not medical advice.
Disclaimer: I'm 73 and I hope to be gone long before this brave new world emerges. The rest of you will be stuck with Larry Ellison ... forever.
You'll delay as many of the diseases of aging as much as you can by doing those things. Packaging their effects in a pill would make you the richest person in history.
Also having good relations with people around you can take you miles.
For myself, I plan to die before I hit 60. I'm not going to spend decades in pain and misery for no reason, life already sucks without my body falling apart. Kevorkian diet all the way!