I'd helped my friend set up 2FA on their email and other socials in the past, but this one must have slipped through the cracks, so the password compromise let them take over the kingdom.
Any human review of his account would be able to tell in a matter of seconds that it's a textbook account hack, but he's emailed the formal support channels to no avail so far. If anyone works for Instagram and can help, he (and I) would really appreciate the help as his account dates back to 2012 and of course, the photos aren't backed up! Thanks for reading.