I expect Bitcoin to take a large hit. I expect the amount of mining to drastically drop as it becomes unprofitable to do so. This might lead to a 51% event and a hard fork and/or collapse.
In the long term, if it survives, I expect BitCoin to emerge with a much lower value. This can be either because of a new lower equilibrium found with the cost of mining, OR as alternatives to proof of work are adopted.
However -- The US dollar might take a huge hit as well due to the ever increasing consequences of our outsourcing of our supply chain here in the US. It may be that in terms of numbers (not value of goods purchased) you might find the BTC-USD price remaining relatively stable as the dollar inflates away it's value.
Also, in 10 yrs or so you will see the space being dominated by a few big players. The big players will offer services that will be hard to pass up by customers so they will flock to them. The idea of decentralization will still be part of the space but a small part. The big players will be involved on the protocol's definition with the stated goal of improving the protocol for all but they a really looking out for their interest. They want to make sure the protocols don't created problems for them as they change.
Something that must happen is that the services must get to a point where customers find it very easy to use. So any company that can create services that are fool proof will win over customers and be one of the big players.
Other than that, I think the technologies will always be niche. At the end of the day its cheaper to have a single mutable source than many different immutable sources with a resolution mechanism, and economics tends to move towards the cheaper substitute (also cheaper in terms of complexity, many decisions are made out seeking simplicity, even if the more complex option is the optimal choice).