As I mentioned before [2], snap is a hill I'm ready to die on, so after being a user for almost 15 years, I'm parting ways with Canonical. I respect their (likely commercial) decision to push forward with snap, but it's a compromise I'm not willing to accept, so I'm actively testing Debian and POP!_OS. I'm leaning towards the latter.
[1] https://www.theregister.com/2022/04/28/pop_os_2204_is_here/
There is some software installed by default on 22.04 by snap that has no Ubuntu-provided alternative "deb" package. This includes firefox and the "Ubuntu Software" store app (installed by default) and LXD (not installed by default, but if you want to use it, there is no deb package). If you're not using any such snap software, it may not matter. In some cases you may be able to install software through some other non-snap method from a non-Ubuntu source (e.g. you may be able to install firefox using the standard linux installer, though I have not tried that).
With regards to the Ubuntu live kernel update feature, this is powered by the 'canonical-livepatch' snap. When you run "ua enable livepatch" it installs the snap. Without snap, it won't work, hence you won't get live patches. Livepatches are not automatically enabled by default for a standard install on your own hardware, you need to attach it to your ubuntu account with "ua attach" and then "ua enable livepatch" (it's free for 3 personal machines and requires a paid subscription otherwise). You can read more about that at https://ubuntu.com/security/livepatch. The snap package is the only canonical-livepatch client package hence if you removed snapd you would lose access to use livepatches.
Disclaimer: I work for Canonical (Ubuntu).
Edit: Another poster suggested PopOS - that's probably a less radical change.
Linux Mint has a Debian edition that I've been using for awhile now. It's quite nice! https://www.linuxmint.com/download_lmde.php
I hate hate hate hate hate snap. It's a bad idea, badly done.
Long answer: if you want to use Firefox you’ll have to find an unsupported way of running it. Chromium is also a snap in the repositories ( it is a meta package)
I’ve had a good experience with setting up the Brave repository from the official website and using that.
Live patch is a commercial product and I don’t think many home users of Ubuntu use it.
If doing a fresh install is viable for you, I recommend PopOS 22.04 they ship and support their own build of Firefox as a native package and flatpak and flathub are configure out of the box and are preferable to snaps (but not forced on you)
No flatpak either.