I have several systems in there now that just do BOINC compute of various forms. If I have surplus power, I run them, if I don't, I don't. I really need to move them outside in the summer, though - I spend a lot of energy on air conditioning to keep the inside cool.
Pick a project you find useful and go! It'll chew as much idle CPU as you let it!
If electricity isn't a concern, and you have a lot of CPU power, perhaps you can get into the cloud business. While AWS and Azure have come to dominate the market, there are still smaller providers (usually called "VPS" providers) that are doing well for themselves.