IF you focus on email, lots of clients are better. If you seek integration into calendar services, you can't beat Google Mail.
I am running the current spec outlook on OSX, and its a dog, slow, lumpy, badly designed. Mail.app has problems but its better by far, but harder to configure in some ways.
Maybe outlook is the embrace-extend-control example we need to cite, when people ask why we worry about the modern Microsoft?
1. It integrates best with their company groupware server, which is probably some variant of Exchange.
2. A lot of people (inexplicably to me) seem to really like using Outlook. They understand it well, the UX is relatively static, and it is powerful.
If you're just comparing basic email and calendar, I'm not sure. For enterprise, if you don't already have a competing product, taking on Outlook is a big gamble. For casual users, built-in email clients are probably good enough for most users.