For instance, ever since I found out about Vimium and CVim, I can't think of a better way to browse the web using keyboard (what the heck was I doing all those years before that?!)
Another example: I've set up many customized keyboard shortcuts (some use macros) in Word that have made a significant difference on my productivity and how much I enjoy typing in the software.
I use "sudo -i" instead of "sudo su -"
in vi, I use "ZZ" instead of ":wq!" to save and exit.
bonus: I save time typing repetitive things into the shell by making cut and paste capable stanzas in documentation like this:
cat << EOF > newfilename
...
EOF