I have noticed a lot of discussions related to life science topics on HN tend to be overly speculative, poorly grounded in empirical research, or simply pseudoscientific. The level of biochemical knowledge here is rather inconsistent compared to say, CS or physics. Most of the time the conversation is merely parroting existing popular science buzzwords, with no real understanding of scale, difficulty, or time to market. I hope by making a new platform that is life science focused rather than on software (yes I am aware HN isn't exclusively for software discussions only), there can be greater agglomeration effects for biotechnology research, akin to what hacker news have done for promoting internet startups.
If the post has less than 20 or 30 comments, it is possible to reply to the interesting comments that are wrong or are asking for more information. Sometimes the article has big mistakes, and it is still possible to make a toplevel comment explaining the errors.
When the post already has 100 comment, usually the conversation derrailed and the main discussion is if it's possible to use an Em-Drive inside a Warp-Drive bubble to make a Start Treck teleporter, or something like that.
I'm not an specialist in Biology, so repliying in biologial threads is more difficult. Please ramian here and answer questions in your area of knowdledge.
There are various science subreddits with large readerships but quality there is also mixed. Although you do see some high quality discussions.
I think you will have a challenge incentivizing high quality scientific discussion because the people with the acumen to have them are busy actually doing science.
If you get that down, I think that many people would be interested in a biology-focused HN-like site. Getting the right people to join is important, too. HN started out with some high-level folk, who set the tone for what this site is.
Good luck!
The structure then could be just a news feed of important bio stories and there is expert discussion locally then you click and it links to HNs copy with discussion.
I think plenty of people would be happy to have a HN type platform for whatever their area of interest is, given it's moderated well and has a healthy, invested community.
Good luck with 1 and 1000x Good luck with 2.
In general, the more, the better. https://lobste.rs/ and https://www.designernews.co/ are still active after several years, their community is just smaller.
But that's also good because it hasn't be done yet and needs doing.