Everything's plain vanilla for me. It's a lot less code, way easier to manage and is a lot faster (as long as you know what you are doing). I work on rather niche products so there are a lot of components that need to be designed, engineered and built from scratch anyways (e.g. very few ready made modules/components are an import away).
I'd hope that actually knowing core javascript, the DOM and APIs must make you a more valuable dev.