What are the moonshots ideas to fight SARS-COV-2?

We are unable to adequately model the genetic and biological aspects of humans and how individual components (of a drug) affect those genetic/ biological components individually and in concert.

imagine someone who was crazy enough to say... we will try to 10x everything we have done to date and FINALLY do computer simulations at an unheard of scale and complexity and MAKE the modeling/digital testing breakthroughs that current people said were impossible.