What are solutions for developing itch scratch desktop program?

I'm looking for something that is self contained with GUI drawing tools, graph generator, a database, and an easy way to call server API's. I'd like to not have to depend on a web or database server.

The programs developed are not meant to be distributed as professional solutions or run unattended. It's more along the lines of exploring data, scraping/crawling web pages and consuming internet API's then being able to show tabulated and graph results.

Thanks.