"He has a systemic infection."
"The new police chief had to address systemic corruption."
Systematic describes something that was thorough and intentional, methodical, or implemented according to a plan. It is the older word, having entered English around 1670. "Doctors began a systematic treatment plan."
"Ending systematic discrimination was his first goal."
"The Doctors began a systematic treatment plan to treat the patient's systemic infection."
"Systemic corruption was found to be the root cause of systematic discrimination throughout the department"